何荣祥

发布者:陈红梅发布时间:2021-03-25作者:浏览次数:1076

何荣祥  博士,副研究员,硕士生导师

电话:027-84223798

E-mail: herx@jhun.edu.cn

地址:江汉大学交叉学科研究院,430056

2004年至2013年在武汉大学物理科学与技术学院完成本科到博士的修读。20108月至20118月在香港理工大学应用物理系严锋教授课题组合作交流。201310月入职江汉大学,加入交叉学科研究院纳米生物医学工程中心,在微流控芯片及癌症诊断等方面开展研究工作。

研究领域:

新型有机无机半导体传感器;癌症筛查及诊断;微流控芯片系统集成开发及应用。

科研项目

1.主持。基于微流控芯片的外泌体分离和检测及其在癌症检测和治疗中的应用研究,武汉市科技局应用基础前沿项目,2019.72021.12.

2.主持。基于3维微纳结构微流控芯片胎儿有核红细胞捕获和分离的早期无创产前基因诊断,国家自然科学基金应急管理项目2018.1.12018.12.31. 已结题。

3.主持。国家自然科学基金青年基金项目,基于微纳结构和电场多模块相耦合的3维微流控芯片CTCs检测研究,2015.1.12017.12.31.已结题。

发表论文

2020

36.Y. Wang, H.Q. Sang, W.Q. Zhang, Y.Y. Qi, R.X. He, B.L. Chen, W.W. Sun*, X.Z.Zhao, D.J. Fu*, Y.M. Liu*, Electrophoretic Deposited Black Phosphorus on 3D Porous Current Collectors to Regulate Li Nucleation for Dendrite-Free Lithium Metal Anodes, ACS Applied Materials & Interfaces,2020,DOI:10.1021/acsami.0c16430.

35. C.H. Chen, R.X. He, Z.T. Zhang and Y. Chen,Dual-recognition-based determination of ctDNA via the clamping function of peptide nucleic acid and terminal protection of small-molecule-linked DNA, Analyst,2020, doi:10.1039/D0AN01305F.

34. He, R.X., Ruan, M.L., Qi, Y.Y., Liu, H.N., Zhang, Z.T., Chen, C.H., Cao, Y.P., Liu, Y.M. and Chen, Y. (2020), Engineering of Droplet Charges in Microfluidic Chips. Adv. Eng. Mater., 2020, doi: 10.1002/adem.201901521.

33. Li, C.; Wang, B.; Wan, H.; He, R.; Li, Q.; Yang, S.; Dai, W.; Wang, N. An Integrated Optofluidic Platform Enabling Total Phosphorus On-Chip Digestion and Online Real-Time Detection. Micromachines, 2020, 11, 59.

2019

32.Wang, S. F., Jin, J. J., Qi, Y. Y., Liu, P., Xia, Y., Jiang, Y., He, R.X., Chen, B. L., Liu, Y. M., Zhao, X.Z., δ‐CsPbI3Intermediate Phase Growth Assisted Sequential Deposition Boosts Stable and High‐Efficiency Triple Cation Perovskite Solar Cells. Adv. Funct. Mater. 2019, 1908343.

31.Cai B., Ji T.-T., Wang N., Li X.-B., He R.X., Liu W., Wang G., Zhao X.-Z. *, Wang L. *, Wang Z.*, A microfluidic platform utilizing anchored water-in-oil-in-water double emulsions to create a niche for analyzing single non-adherent cells. Lab on a Chip, 2019, 19422-431.

2018

30.Zaizai Dong, Chuanhao Tang, Libo Zhao, Jiachao Xu, Yayun Wu, Xiaojun Tang,Wei Zhou, Rongxiang He, Rong Zhao, Li Xu, Zhen Zhang, and Xiaohong Fang*, A Microwell-Assisted Multiaptamer Immunomagnetic Platform for Capture and Genetic Analysis of Circulating Tumor Cells,Advanced Healthcare Materials,20181801231.

29.Wu, X., Xiao, T. Y., Luo, Z., He, R. X., Cao, Y. P., Guo, Z. Z., Zhang, W. Y., & Chen, Y. A micro-/nano-chip and quantum dots-based 3D cytosensor for quantitative analysis of circulating tumor cells. Journal of Nanobiotechnology, 2018, 16: 65

28.Xia, Y., Xiong, W.-S., Jiang, Y., Zhou, S.-Y., Hu, C.L., He, R.X., Sang, H.-Q., Chen, B., Liu, Y., & Zhao, X.-Z. ,Controllable in-situ growth of 3D villose TiO2 architectures on carbon textiles as flexible anode for advanced lithium-ion batteries. Materials Letters, 2018,229, 122-125.

27. Xiong, W.-S., Jiang, Y., Xia, Y., Qi, Y., Sun, W., Hu, C.L., He, R.X., Chen, B., Liu, Y., & Zhao, X.-Z. , A sustainable approach for scalable production of α-Fe2O3 nanocrystals with 3D interconnected porous architectures on flexible carbon textiles as integrated electrodes for lithium-ion batteries. Journal of Power Sources, 2018,401, 65-72.

26. C.H. Chen, Y.N. Zhang, Z.T. Zhang, R.X. He, Y. Chen,Fluorescent Determination of Glucose Using Silicon Nanodots, Analytical letters,2018, 51, 2895-2905..

26. Q.Q Liao, S.K. Zhao, B. Cai, R.X. He, L. Rao, Y. Wu, S.S. Guo, Q.Y. Liu, W. Liu, X.Z. Zhao,Biocompatible fabrication of cell-laden calcium alginate microbeads using microfluidic double flow-focusing device, Sensors and Actuators: A. Physical2018279313-320.

24. H.N. Liu, M.L. Ruan, J.R. Xiao, Z.T. Zhang, C.H. Chen, W.Y. Zhang, Y.P. Cao, R.X. He*, Y.M. Liu*, and Y. Chen*,TiO2 Nanorods Arrays with Mesoscopic Micro-nano Interfaces for In Situ Regulation of Cell Morphology and Nucleus Deformation, ACS Applied Materials & Interfaces,2018, 10, 66-74.

2017

23. Z.T. Zhang, M.L. Ruan, H.N. Liu, Y.P. Cao, and R.X. He*, Fabrication of large size alginate beads for three-dimensional cell-cluster culture. AIP Conference Proceeding 1864,2017, 020138. (EI)

22. Zheng Z.Q., Ye H.X., Wang J., Zhang T.Y., You Q.L., Li H.H., He R.X., Chen Y., Zhang W.Y. * and Cao Y.P. *, Visible-light-controllable drug release from multilayer-coated microneedles, Journal of materials chemistry B, 2017, 5, 7014-7017.

21.Xia Y., Xiong W.S., Jiang Y., Sun W.W., Sang H.Q., He R.X., Tai Q.D., Chen B.L., Liu Y.M. and Zhao X.Z.,Multi-walled carbon nanotubes induced a controllable TiO2morphology transformation for high-rate and long-life lithium-ion batteries. RSC advances, 2017, 7, 21988-21996.

20. He, Z.B., Guo, F., Feng, C., Cai, B., Lata, J.P., He, R.X., Huang, Q.Q., Yu, X.L., Rao, L., Liu, H.Q., Guo, S.S., Liu, W., Zhang, Y.Z., Huang, T.J., Zhao, X.Z., 2017. Fetal nucleated red blood cell analysis for non-invasive prenatal diagnostics using a nanostructure microchip. Journal of Materials Chemistry B, 2017, 5226-235.

2016

19. Wang, S., Qu, D., Jiang, Y., Xiong, W.S., Sang, H.Q., He, R. X., Tai, Q., Chen, B., Liu, Y., Zhao, X.Z., Three-Dimensional Branched TiO2 Architectures in Controllable Bloom for Advanced Lithium-Ion Batteries. ACS Applied Materials & Interfaces,2016, 8, 20040-20047.

18. Huang, Q.Q., Cai, B., Chen, B.L., Rao, L., He, Z.B., He, R.X., Guo, F., Zhao, L.B., Kondamareddy, K. K., Liu, W., Guo, S.S. and Zhao, X.-Z., Efficient Purification and Release of Circulating Tumor Cells by Synergistic Effect of Biomarker and SiO2@Gel-Microbead-Based Size Difference Amplification. Advanced Healthcare Materials, 2016,5,1554-1559.

17. B. Cai, R.X. He, X.L. Yu, L. Rao, Z.B He, Q.Q. Huang, W. Liu, S.S. Guo, and X.Z. Zhao, 3D valve-based controllable PDMS nozzle for dynamic modulation of droplet generation, microfluidics and nanofluidics, 2016, 20,1-10.

16.R.X. He*, J.R. Xiao, M.L. Zhang, Z.T. Zhang, W.Y. Zhang, Y.P. Cao, Y.M. Liu*, and Y. Chen*, Artificial honeycomb-inspired TiO2 nanorod arrays with tunable nano/micro interfaces for improving poly(dimethylsiloxane) surface hydrophobicity. Journal of materials science, 2016, 51, 2935-2941.

2015

15.Li, N.; Xiao, T.; Zhang, Z.; He, R.; Wen, D.; Cao, Y. *; Zhang, W. *; Chen, Y., 3D graphene oxide microchip and Au-enwrapped silica nanocomposite-based supersandwich cytosensor toward capture and analysis of circulating tumor cells. Nanoscale, 20157,16354-16360.

14.W.Q. He, J.R. Xiao, Z.T. Zhang, W.Y. Zhang, Y.P. Cao, R.X. He* and Y. Chen*, One step electroplating 3D template with gradient height to enhance micromixing in microfluidic chips, Microfluidics and Nanofluidics, 2015, 19, 829-836.

13.J.R. Xiao, W.Q. He, Z.T. Zhang, W.Y. Zhang, Y.P. Cao, R.X. He* and Y. Chen*, PDMS micropillar-based microchip for efficient cancer cell capture, RSC Advances, 2015, 5,52161-52166.

12.Wang, J., Li, J., Li, N., Guo, X.L., He, L., Cao, X., Zhang, W.Y., He, R.X.*, Qian, Z.Y.*, Cao, Y.P.*, Chen, Y., A Bottom-Up Approach to Dual Shape-Memory Effects. Chem. Mater. 201527, 2439-2448.

2014

11. J. Li, X.Y. Zhang, S.Q. Chen, Q.L. You, R.X. He, J. Shi, Y.P. Cao*, Y. Chen*, Multi-responsive drug release from hydrogen-bonding multilayers containing PEGylated nanoparticles and azobenzenes. J. Mater. Chem. B, 2014, 2, 4422-4425.

10. B.R. Cheng, Z.B. He, L.B. Zhao, Y. Fang, Y.Y. Chen, R.X. He, F.F. Chen, H.B. Song, Y.L. Deng, X.Z. Zhao, B. Xiong, Transparent, biocompatible nanostructured surfaces for cancer cell capture and cultureInt. J. Nanomedicine, 2014, 9, 2569-2580.

9.Q. Huang, B. Chen, R.X. He, Z. He, B. Cai, J. Xu, W. Qian, H. L. Chan, W. Liu, S. Guo, X.-Z. Zhao* and J. Yuan*, Capture and Release of Cancer Cells Based on Sacrificeable Transparent MnO2 Nanospheres Thin Film, Adv. Healthcare Mater., 2014,3,1420-1425.

8. Wang, J., Ni, C., Zhang, X., Zhang, Z., You, Q., He, R., Shi, J., Liu, J., Cao, Y., Chen, Y., 2014. Photoswitchable Layer-by-Layer Nanostructured Multilayer Films for Drug Delivery. Journal of Nanoengineering and Nanomanufacturing,2014,4,316-320.

7. B. Cai, F. Guo, L.B. Zhao, R.X. He, B.R. Chen, Z.B. He, X.L. Yu, S.S. Guo, B. Xiong, W. Liu* and X.Z. Zhao, Disk-like Hydrogel bead based Immuno- fluorescence Staining toward Identification and Observation of Circulating Tumor Cells, Microfluidics and Nanofluidics, 2014,16,29-37.

2013年以前

6. R.X. He, L.B. Zhao, Y.M. Liu, N.G. Zhang, B. R. Chen, Z. B. He, B. Cai, S. Z. Li, W. Liu, S.S. Guo, Y. Chen, B. Xiong, and X.Z. Zhao, Biocompatible TiO2 nanoparticle-based cell immunoassay for circulating tumor cells capture and identification from cancer patients, Biomedical microdevice, 2013, 15,617-626.

5.S. Hou, L. Zhao, Q. Shen, J. Yu, C. Ng, X. Kong, D. Wu, M. Song, X. Shi, X. Xu, W.-H. OuYang, R.X. He, X.Z. Zhao, T. Lee, F. C. Brunicardi, M. A. Garcia, A. Ribas, R. S. Lo and H.-R. Tseng, Polymer Nanofiber-Embedded Microchips for Detection, Isolation, and Molecular Analysis of Single Circulating Melanoma Cells. Angew. Chem. Int. Ed., 2013, 52,3379-3383.

4.X.L. Yu, R.X. He, S.S. Li, B. Cai, L.B. Zhao, L. Liao, W. Liu, Q. Zeng, H. Wang, S.S. Guo* and X.Z. Zhao, Magneto-Controllable Capture and Release of Cancer Cells by Using a Micropillar Device Decorated with Graphite Oxide-Coated Magnetic Nanoparticles, Small, 2013, 9, 3895-3901.(Co-first author

3. R. X. He, P. Lin, Z. K. Liu, H. W. Zhu, X. Z. Zhao, H. L. W. Chan and F. Yan, Solution-Gated Graphene Field Effect Transistors Integrated in Microfluidic Systems and Used for Flow Velocity Detection. Nano Lett., 2012, 12, 1404-1409.

2. R.X. He, M. Zhang, F. Tan, P. H. M. Leung, X.-Z. Zhao, H. L. W. Chan, M. Yang and F. Yan,Detection of bacteria with organic electrochemical transistors.J. Mater. Chem., 2012, 22, 22072-22076.

1. N. A. Zhang, Y. L. Deng, Q. D. Tai, B. R. Cheng, L. B. Zhao, Q. L. Shen, R. X. He, L. Y. Hong, W. Liu, S. S. Guo, K. Liu, H. R. Tseng, B. Xiong and X. Z. Zhao, Electrospun TiO2 Nanofiber-Based Cell Capture Assay for Detecting Circulating Tumor Cells from Colorectal and Gastric Cancer Patients. Adv. Mater.,2012, 24, 2756-2760.